Intron Size and Exon Evolution in Drosophila
- 1 May 2005
- journal article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 170 (1), 481-485
- https://doi.org/10.1534/genetics.104.037333
Abstract
We have found a negative correlation between evolutionary rate at the protein level (as measured by dN) and intron size in Drosophila. Although such a relation is expected if introns reduce Hill-Robertson interference within genes, it seems more likely to be explained by the higher abundance of cis-regulatory elements in introns (especially first introns) in genes under strong selective constraints.Keywords
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