Effect of Morphine and n-Allylnormorphine on Cerebral Hemodynamics and Oxygen Metabolism
- 1 March 1957
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 15 (3), 379-384
- https://doi.org/10.1161/01.cir.15.3.379
Abstract
The cerebral metabolic response to intravenously administered morphine was studied in human volunteers. Cerebral blood flow and cerebral vascular resistance were not altered by this drug although cerebral oxygen uptake was markedly depressed as a result of a decreased extraction of oxygen from the blood circulating through the brain. This response was rapidly reversed following the administration of n-allylnormorphine.Keywords
This publication has 6 references indexed in Scilit:
- SOME EFFECTS OF N–ALLYLNORMORPHINE ON NORMAL SUBJECTS AND A REVIEW OF THE LITERATUREAnesthesiology, 1955
- THE EFFECT OF THEOPHYLLINE WITH ETHYLENEDIAMINE (AMINOPHYLLINE) AND CAFFEINE ON CEREBRAL HEMODYNAMICS AND CEREBROSPINAL FLUID PRESSURE IN PATIENTS WITH HYPERTENSIVE HEADACHESThe American Journal of the Medical Sciences, 1952
- BLOOD FLOW AND OXYGEN CONSUMPTION OF THE HUMAN BRAIN DURING ANESTHESIA PRODUCED BY THIOPENTALAnesthesiology, 1951
- Protective Action of N-Allyl-Normorphine Against Respiratory Depression Produced by Some Compounds Related to Morphine.Experimental Biology and Medicine, 1950
- THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN: THEORY, PROCEDURE AND NORMAL VALUES 1JCI Insight, 1948
- RESPIRATION IN THE CENTRAL NERVOUS SYSTEMPhysiological Reviews, 1939