Thermic effect of food during graded exercise in normal weight and obese men

Abstract

The thermic effect of food during incremental cycle ergometer exercise was compared in six normal weight and six obese men (mean ± SEM 104 ± 5% and 160 ± 11% ideal body weight, respectively). Graded exercise tests were performed after a 12-h fast and 60 min after the start of a 910 kcal mixed meal, on separate days. The thermic effect of food during exercise, which is the fed minus the fasting oxygen consumption (V̇O₂), was significantly greater for the normal than the obese men at submaximal intensities from 0 (unloaded cycling) to 100 W (p < 0.05). The mean slope of the regressions of V̇O₂ (ml · min⁻¹) on power output (W), which reflects the rate of increase in energy expended relative to increases in external work performed, did not differ significantly between the fed and fasting conditions for either gjpup, but the mean (±SEM) intercept was significantly higher for the normal, but not the obese men, in the fed than the fasting state (599 ± 53 versus 497 ± 47 ml O₂ · min⁻¹ for the normal men and 819 ± 126 versus 821 ± 145 ml O₂ · min⁻¹ for the obese men). These results indicate that the thermic effect of food during exercise, which is virtually absent in the obese men, does not increase significantly across submaximal power outputs for the normal men and therefore does not reflect a significant reduction in efficiency.