Antigens of cowpox virus
- 1 March 1962
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 60 (1), 41-49
- https://doi.org/10.1017/s0022172400039292
Abstract
Cowpox soluble antigen is shown by gel-diffusion studies to contain at least nine precipitable substances whose presence is induced by virus infection. One of these substances, pattern component d, is not produced in white cowpox infections, and its production in vaccinia infection can be inferred only from the presence of small amounts of anti-d in anti-vaccinia sera.Comparison of cowpox with vaccinia has led to the recognition of a further line pattern component f which is readily demonstrated as a soluble precipitable substance in simple buffer extracts of vaccinia-infected tissue, but is demonstrated in extracts of cowpox-infected tissue only with difficulty; anti-f antibody is readily detected in antisera prepared against cowpox, white cowpox, and vaccinia.Keywords
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