[18F] fluorine labeled aliphatic amino acids

Abstract

The synthesis of 4‐[¹⁸F] fluoroproline is described, but attempts to prepare 3‐[¹⁸F] fluoroalanine failed. In the synthetic pathway to this compound different routes are investigated to make a labeled precursor, viz [¹⁸F] fluoromethyliodide, which, however, were unsuccessful.