Chromatographic Analysis of Water and Wine Samples for Phenolic Compounds Released from Food-Contact Epoxy Resins

Abstract

Food-contact epoxy resins can release phenolic compounds such as phenol, m-cresol, bisphenol F, bisphenol A, 4-tert-butylphenol, bisphenol F diglycidyl ether (BFDGE), and bisphenol A diglycidyl ether (BADGE) into foodstuffs. A validated high-performance liquid chromatographic method with fluorometric detection is described for the simultaneous analysis of these compounds in wine and mineral water. Sample preparation by solid—liquid extraction enables detection limits of 2.5 μg/L in wine and 0.25 μg/L in mineral water to be achieved. Recovery rates are close to 100%, except for BFDGE and BADGE (around 60% in wine and 75% in mineral water).