COMPARISON BETWEEN THE DIRECT CAPILLARY TUBE LEUCOCYTE MIGRATION TECHNIQUE (LMCT)AND THE DIRECT AGAROSE LEUCOCYTE MIGRATION TECHNIQUE (LMAT)AS INDICATORS OF TUMOUR-DIRECTED CELL-MEDIATED HYPERSENSITIVITY (TCMH)IN PATIENTS WITH RENAL CARCINOMA
- 1 April 1976
- Vol. 31 (2), 141-158
- https://doi.org/10.1111/j.1398-9995.1976.tb01488.x
Abstract
A comparison was made between the direct capillary tube leucocyte migration technique (LMCT) and the direct agarose leucocyte migration technique (LMAT) using crude homogenates of tumour tissue as antigen in patients with renal carcinoma. A state of specifically altered reactivity of leucocytes from patients with renal carcinoma as compared with normal control persons towards allogeneic hypernephroma extracts could be detected in the LMCT but not in the LMAT. The reactivity in the LMCT was manifest at protein concentrations of 300 and 400 mug/ml. The study indicates that in contrast to the LMCT, the LMAT cannot be used for detection of TCMH towards allogeneic hypernephroma tissue extracts in patients with renal carcinoma.Keywords
This publication has 13 references indexed in Scilit:
- EFFECT OF BASIC ENCEPHALITOGENIC PROTEIN AND SOME PEPTIDES DERIVED FROM IT ON THE MIGRATION IN AGAROSE GEL OF LEUKOCYTES FROM PATIENTS WITH MULTIPLE SCLEROSIS, OTHER NEUROLOGICAL DISEASES, OR CARCINOMAActa Neurologica Scandinavica, 2009
- Cell-Mediated Immunity to a Serologically Defined (SD) HL-A Antigen Panel in Kidney-Transplanted PatientsScandinavian Journal of Immunology, 1975
- LEUKOCYTE MIGRATION IN AGAROSE, A STUDY ON MULTIPLE SCLEROSISAllergy, 1975
- The dose-related effect of tumour extract on the in vitro migration of leucocytes from patients with renal carcinomaEuropean Journal of Cancer (1965), 1975
- In vitro demonstration of cellular hypersensitivity to tumour antigens by means of the leucocyte migration technique in patients with renal carcinomaEuropean Journal of Cancer (1965), 1974
- INHIBITION OF LEUCOCYTE MIGRATION IN MAN BY THE AGAROSE PLATE TECHNIQUE USING PROTEIN PURIFIED DERIVATIVES (PPD) FROM THREE DIFFERENT SOURCESAllergy, 1974
- ON THE REACTIVITY OF HUMAN LEUKOCYTES TO PPD IN CLAUSEN'S AGAROSE MIGRATION TECHNIQUEAllergy, 1974
- COMPARISON BETWEEN CAPILLARY TUBE AND AGAROSE MIGRATION TECHNIQUE IN THE STUDY OF HUMAN PERIPHERAL BLOOD LEUKOCYTESAllergy, 1973
- Standardization of the Leucocyte Migration TestInternational Archives of Allergy and Immunology, 1973
- TUBERCULIN‐INDUCED MIGRATION INHIBITION OF HUMAN PERIPHERAL LEUCOCYTES IN AGAROSE MEDIUMAllergy, 1971