AZA STEROIDS: III. SYNTHESIS OF 11-AZA STEROIDS—A NOVEL CLASS OF STEROIDAL SAPOGENIN ANALOGUES
- 1 April 1963
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 41 (4), 958-965
- https://doi.org/10.1139/v63-135
Abstract
The cyclization of a 9,12-seco-11-nor keto acid in the hecogenin series in the presence of benzylamine and anhydrous ammonia is described. The benzylamine reaction follows an unusual course whereas the ammonia reaction proceeds normally to provide an enol lactam. The sequence represents the first synthesis of an 11-aza derivative in the steroidal sapogenin series.This publication has 10 references indexed in Scilit:
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