Inability of Growth Hormone to Prevent the Anemia which Follows Hypophysectomy.

Abstract

Admn. of doses of growth hormone in doses sufficient to maintain a normal rate of growth for 30 days in 17 female rats of the Long-Evans strain (controlled by an equal number of normal and of uninjected hypophysectomized rats) failed to prevent the development of the anemia which characteristically follows hypophysectomy. Values for hematocrit, hemoglobin and red cell volume of the growth hormone-injected hypophysectomized rats were identical with the values in the hypophysectomized controls and markedly lower than the values in the normal controls.