Synthetic Applications of Double Functionalization by Cooperating Sulfur- and Oxygen-Containing Substituents

Abstract

This review describes the cooperating effect of unsymmetrical disubstitution by sulfur- and oxygen-containing functional groups which gives rise to unique reactivities and synthetic utilities. 1. Introduction 2. Geminal Disubstitution 2.1. Novel One-Carbon Homologation Reagents 2.2. α-Acetoxy Ethers 2.3. Other Syntheses Following the One-Carbon Homologation 3. Vicinal Disubstitution 4. Allylic Disubstitution 5. Concluding Remarks