Glucose-stimulated Preproinsulin Gene Expression and Nucleartrans-Location of Pancreatic Duodenum Homeobox-1 Require Activation of Phosphatidylinositol 3-Kinase but Not p38 MAPK/SAPK2
Open Access
- 1 May 2000
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 275 (21), 15977-15984
- https://doi.org/10.1074/jbc.275.21.15977
Abstract
No abstract availableKeywords
This publication has 50 references indexed in Scilit:
- Exocytosis of Insulin Promotes Insulin Gene Transcription via the Insulin Receptor/PI-3 Kinase/p70 s6 Kinase and CaM Kinase PathwaysMolecular Cell, 1998
- Purification of the β-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cellsProceedings of the National Academy of Sciences, 1996
- The Insulin Gene Promoter: A Simplified NomenclatureDiabetes, 1995
- Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes.Proceedings of the National Academy of Sciences, 1994
- Glucose modulates the binding activity of the β-cell transcription factor IUF1 in a phosphorylation-dependent mannerBiochemical Journal, 1994
- Electrophysiology of the pancreatic β-cellProgress in Biophysics and Molecular Biology, 1989
- Effects of D-glucose, L-leucine, and 2-ketoisocaproate on Insulin mRNA Levels in Mouse Pancreatic IsletsDiabetes, 1986
- Translational control of proinsulin synthesis by glucoseNature, 1980
- The effect of sugars on (pro)insulin biosynthesisBiochemical Journal, 1978
- Insulin BiosynthesisPublished by Elsevier ,1972