Inhibition of crown-gall tumor formation on potato discs by cyclic-AMP and prostaglandins E1 and E2

Abstract
Cyclic-AMP was found to inhibit the induction of crown-gall tumors on potato discs by as much as 60%. This inhibition could be obtained when cyclic-AMP was added up to 10 hr after inoculation of the potato discs with a tumor inducing strain of Agrobacterium tumefaciens. Similar results were obtained with prostaglandins E1 and E2. Some of the implications of these results will be discussed.

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