Optical microangiography provides depth-resolved images of directional ocular blood perfusion in posterior eye segment

Abstract

In this paper, we demonstrate that the optical microangiography (OAMG) is capable of depth-resolved imaging of directional blood perfusion within both retinal and choroid in the posterior segment of human eye. The study uses an OMAG system operating at $840nm$ with an imaging speed at 27,000 A-scans per second. Sequentially registered multiple OMAG projection maps of small areas $(∼1mm×1mm)$ are combined to provide directional blood flow images for a larger field of view. It takes $∼3.7sec$ to image a small area $(1×1mm2)$, and $∼2.5min$ for a larger field $(3×3mm2)$. Finally, we show superior performance of OMAG in providing functional images of capillary level microcirculation at different depths of retina and choroid that correlate well with the standard retinal pathology.