Proton transport and cell function.
- 1 February 1984
- journal article
- review article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 73 (2), 285-290
- https://doi.org/10.1172/jci111212
Abstract
The past five years have witnessed an explosion of information on the many and varied roles of H+ transport in cell function. H+ transport is involved in three broad areas of cell function: (a) maintenance and alteration of intracellular pH for initiation of specific cellular events, (b) generation of pH gradients in localized regions of the cell, including gradients involved in energy transduction, and (c) transepithelial ion transport. These processes each involve one or more of several H+ translocating mechanisms. The first section of this review will discuss these H+ translocating mechanisms and the second part will deal with the cellular functions controlled by H+ transport.Keywords
This publication has 65 references indexed in Scilit:
- Effects of insulin upon ion transportBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1983
- Energy coupling to ATP synthesis by the proton-translocating ATPaseThe Journal of Membrane Biology, 1982
- Proton/hydroxyl transport in gastric and intestinal epitheliaThe Journal of Membrane Biology, 1982
- An ATP-driven proton pump in brush-border membranes from rat renal cortexThe Journal of Membrane Biology, 1982
- Chloride Uptake by Brush Border Membrane Vesicles Isolated from Rabbit Renal CortexJCI Insight, 1980
- The internal pH of mast cell granulesFEBS Letters, 1980
- Transport of auxin (indoleacetic acid) through lipid bilayer membranesThe Journal of Membrane Biology, 1980
- Existence of electrogenic hydrogen ion/sodium ion antiport in Halobacterium halobium cell envelope vesiclesBiochemistry, 1976
- Oxidative phosphorylation and proton translocation in membrane vesicles prepared from Escherichia coliBiochemical and Biophysical Research Communications, 1974
- Structure of monensic acid, a new biologically active compoundJournal of the American Chemical Society, 1967