Diodrast (I131) whole blood clearance as an index of renal blood flow

Abstract

The whole blood clearance of Diodrast (I¹³¹) following a single intravenous injection was used to estimate renal blood flow. This method was compared to renal blood flow simultaneously determined by the PAH constant infusion technique. A correlation coefficient of 0.930 was found. The Diodrast clearance method is recommended because it is simple and rapid, and it avoids the necessity for urine collection.