Abstract
THE following 3 case studies, related experimental data and review of the recent literature introduce a new clinical concept, that of primary meningoencephalitis due to the the free-living, soil ameba, commonly referred to as acanthameba (species). It is suggested that in these 3 cases there may be a common etiologic pattern of intranasal inoculation resulting from prolonged swimming in tepid lake water.Pathological findings in the first 2 cases were presented to the 1964 Scientific Session of the American Society of Clinical Pathologists,1 and Patras and Andujar2 reported similar findings in the brain of an elderly drug addict to the . . .