First use of an untethered, vented electric left ventricular assist device for long-term support.
- 1 June 1994
- journal article
- case report
- Published by Wolters Kluwer Health in Circulation
- Vol. 89 (6), 2908-2914
- https://doi.org/10.1161/01.cir.89.6.2908
Abstract
This report describes the first long-term (505-day) application of the vented electric (VE) HeartMate left ventricular assist device (LVAD) (Thermo Cardiosystems, Inc). The device consists of an abdominally placed, battery-powered titanium blood pump that, in contrast to earlier pneumatically powered systems, allows patients untethered freedom of movement. The batteries last 5 to 8 hours and can be changed on a rotating basis indefinitely. The patient, a 33-year-old man (90 kg, blood type O) with idiopathic cardiomyopathy, experienced end-organ heart failure (New York Heart Association [NYHA] class IV) while he was awaiting heart transplantation. When his hemodynamic criteria met those outlined in the protocol, we implanted the VE-LVAD as a bridge to transplantation. The patient was supported by the device for more than 16 months. His cardiac status returned to NYHA class I, and he was eventually allowed to take day trips outside the hospital as he awaited transplantation. The VE-LVAD enabled the patient to participate in activities such as eating in restaurants, going to movies, and practicing basketball shots. Unfortunately, the patient died suddenly due to a neurological thromboembolic event that occurred on day 503 of VE-LVAD support. The VE-LVAD improved native left ventricular function by chronic unloading, and ventricular remodeling resulted in a more normal configuration anatomically, physiologically, and ultimately, histologically and pathologically.Keywords
This publication has 7 references indexed in Scilit:
- Internal pulsatile circulatory supportThe Annals of Thoracic Surgery, 1993
- Implantation Technique for the HeartMateRLeft Ventricular Assist DeviceJournal of Cardiac Surgery, 1992
- Multicenter clinical evaluation of the HeartMate 1000 IP left ventricular assist deviceThe Annals of Thoracic Surgery, 1992
- Implantable electrical left ventricular assist systems: Bridge to transplantation and futureThe Annals of Thoracic Surgery, 1989
- Staged Cardiac Transplantation: Use of Mechanical Circulatory Support Devices Including the Total Artificial Heart as Bridges to Cardiac TransplantationPublished by S. Karger AG ,1987
- On resting the human heartAmerican Heart Journal, 1966
- EVIDENCE FOR "REBOUND" HYPERCOAGULABILITY AFTER STOPPING ANTICOAGULANTSThe Lancet, 1964