A new immunostimulatory complex (PICKCa) in experimental rabies: antiviral and adjuvant effects
- 1 September 1993
- journal article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 131 (3-4), 307-319
- https://doi.org/10.1007/bf01378634
Abstract
The activity of an immunostimulatory complex (PICKCa) which is widely used against several human diseases in China was tested in experimental rabies prophylaxis. PICKCa protected mice against peripheral infection with both fixed and wild rabies strains. It also enhanced the protective activity of an experimental rabies vaccine injected either before or after rabies infection. PICKCa enhanced both non-specific immune responses and specific immunity including antibody production and cell mediated immunity as assessed by interleukin-2 production.This publication has 27 references indexed in Scilit:
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