A Novel Closed-Circular Mitochondrial DNA with Properties of a Replicating Intermediate
- 1 September 1971
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (9), 2252-2257
- https://doi.org/10.1073/pnas.68.9.2252
Abstract
A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.Keywords
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