Effect of Chitosan on Epithelial Cell Tight Junctions
Top Cited Papers
- 1 January 2004
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 21 (1), 43-49
- https://doi.org/10.1023/b:pham.0000012150.60180.e3
Abstract
Purpose. Chitosan has been proposed as a novel excipient for transepithelial drug-delivery systems. Chitosan is thought to disrupt intercellular tight junctions, thus increasing the permeability of...Keywords
This publication has 15 references indexed in Scilit:
- The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell lineThe Journal of Nutritional Biochemistry, 2002
- Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epitheliaGastroenterology, 2001
- Chitosan: some pharmaceutical and biological aspects - an updateJournal of Pharmacy and Pharmacology, 2001
- Molecular Physiology and Pathophysiology of Tight Junctions I. Biogenesis of tight junctions and epithelial polarityAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2000
- Disruption of epithelial tight junctions is prevented by cyclic nucleotide-dependent protein kinase inhibitorsHistochemistry and Cell Biology, 2000
- Effect of chitosan on epithelial permeability and structureInternational Journal of Pharmaceutics, 1999
- Biomedical and Pharmaceutical Applications of Alginate and ChitosanBiotechnology and Genetic Engineering Reviews, 1999
- Biodegradation and distribution of water-soluble chitosan in miceBiomaterials, 1999
- Molecular structure and assembly of the tight junctionAmerican Journal of Physiology-Renal Physiology, 1998
- Effect of Chitosan on the Permeability of Monolayers of Intestinal Epithelial Cells (Caco-2)Pharmaceutical Research, 1994