Chemo-enzymatic synthesis of a β-mannosyl-containing trisaccharide

Abstract
For the natural substrate GlcNAcGlcNAc-pyrophosphate-dolichyl 2, replacement of dolichyl by phytanyl yields an analogue 3 that acts as an efficient acceptor substrate for a mannosyl transferase, whereas the corresponding lauryl compound 4 was found to be inactive.