COMPOSITE GASTRIC-CARCINOMA - REPORT OF A TUMOR OF THE CARCINOMA-CARCINOID SPECTRUM
- 1 January 1988
- journal article
- research article
- Vol. 112 (1), 91-93
Abstract
A composite tumor of the gastric antrum composed of areas of adenocarcinoma and poorly differentiated carcinoid is described, with histochemical and immunohistochemical documentation of endocrine and nonendocrine differentiation. The neoplasm maintained a composite architecture both within the site of origin and in lymph node metastases. The adenocarcinoma displayed a predominantly tubular architecture with focal sheets of clear cells. The poorly differentiated carcinoid was argyrophilic, chromogranin immunoreactive, and focally serotonin immunoreactive, and contained keratin intermediate filaments in a distinctive distribution suggestive of endocrine differentiation. Among the tumors of the carcinoma-carcinoid spectrum, the composite tumor is less common than either carcinomas with interspersed endocrine cells or carcinoids with interspersed nonendocrine cells.This publication has 13 references indexed in Scilit:
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