Surface-mediated solid-phase reaction. Part 2. Highly selective mono- and di-C-alkylation of 1,3-dicarbonyl compounds on the surface of alumina

Abstract

Highly selective mono- and di-C-alkylation of 1,3-dicarbonyl compounds with different, structurally varied alkyl halides has been achieved in high yields through a simple solvent-free reaction on the surface of alumina impregnated with sodium or potassium alkoxide.