Abstract
A 10-wk study designed to gain some understanding of how to treat patients who have suffered for a long time with headaches that were not alleviated by many attempts at treatment is described. Patients [14] whose chief complaint was this kind of headache were given varying amounts of perphenazine and amitriptyline with the direct suggestion that these drugs would be helpful. Treatment appeared successful for 10 of the 14 patients at 6-mo. and 3-yr follow-up.

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