Abstract
Discusses the bearing of existing evidence in Delphinium, Zea, Ustilago, Lathyrus, and Chlamydomonas on the problem of the stage at which the nucleus affects the cytoplasm. The decisive cases indicate that in the energic or resting stage the nucleus is able to influence the cytoplasm. Suggests further work with those species where dimorphism of pollen grains is brought about by specific genes as a means of determining whether these genic effects occur only after the breakdown of the nuclear membrane.

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