Thrombotic Thrombocytopenic Purpura with C′3Vascular Deposits: Report of a Case

Abstract
Weisenburger, Dennis D., O’Connor, Michael, L., and Hart, M. Noel: Thrombotic thrombocytopenic purpura with C′3 vascular deposits. Report of a case. Am J Clin Pathol 67: 61–63, 1977. A case of thrombotic thrombocytopenic purpura in a young woman in which platelet microthrombi were distributed in small vessels throughout the body is reported. IgM and complement (C′3) were demonstrated in capillary and small arteriole walls by immunofluorescent microscopy. These findings support the findings of a previous case report,2 and are further evidence for a possible primary immune etiology for thrombotic thrombocytopenic purpura.