Sickle cell disease is diagnosed most frequently in the pediatric age group, since clinical symptomatology usually occurs prior to the age of six. However, the diagnosis is seldom made under one year of age. This, of course, is not due to decreased incidence because as genetically determined disorders, both the homozygous state (sickle cell disease ordisease) and the heterozygous state (sickle cell trait ortrait) exist from birth. Mulherin1has shown that cord blood specimens from the newborn that later develops typical electrophoretic patterns of either the heterozygous or homozygous state, will give a positive sickle preparation, utilizing the sodium metabisulfite method. The percentage of red cells demonstrating the sickle phenomenon at birth ranges from 1%-42%. With this in mind, it is not surprising that symptoms may occur at a very early age. Leiken and McCoo2found four cases in the literature and added two of their