Local Cerebral Blood Flow in Rats with Congenital Hydrocephalus
Open Access
- 1 May 1993
- journal article
- Published by SAGE Publications in Journal of Cerebral Blood Flow & Metabolism
- Vol. 13 (3), 531-534
- https://doi.org/10.1038/jcbfm.1993.69
Abstract
Local cerebral blood flow (LCBF) has been measured by [14C]iodoantipyrine quantitative autoradiography in H-Tx rats with inherited congenital hydrocephalus at 10, 21, and 30 days after birth. LCBF at 10 days was uniformly low in all ten brain regions studied and not significantly different between hydrocephalic and age-matched control rats. By 21 days LCBF had increased significantly in control rats. LCBF was significantly lower (−1 min−1 for hydrocephalics and from 100 to 183 ml 100 g−1 min−1 for controls.Keywords
This publication has 28 references indexed in Scilit:
- MR imaging for measurements of ventricles and cerebral cortex in postnatal rats (H-Tx strain) with progressive inherited hydrocephalusExperimental Neurology, 1992
- Cerebrospinal Fluid Pressure in 10-Day-Old Rats with Congenital HydrocephalusEuropean Journal of Pediatric Surgery, 1991
- INHERITED PRENATAL HYDROCEPHALUS IN THE H–Tx RAT: A MORPHOLOGICAL STUDYNeuropathology and Applied Neurobiology, 1988
- Changes in cerebral microvasculature in congenital hydrocephalus of the inbred rat lew/jms: Light and electron microscopic examinationSurgical Neurology, 1987
- STUDIES ON CEREBRAL OXYGEN METABOLISM, BLOOD FLOW, AND BLOOD VOLUME, IN PATIENTS WITH HYDROCEPHALUS BEFORE AND AFTER SURGICAL DECOMPRESSION, USING POSITRON EMISSION TOMOGRAPHYBrain, 1986
- Neuronal effects of experimentally induced hydrocephalus in newborn ratsJournal of Neurosurgery, 1985
- Low-Cost Microcomputer-Based DensitometerJournal of Cerebral Blood Flow & Metabolism, 1985
- Pathogenesis of normal-pressure hydrocephalus preliminary observationsSurgical Neurology, 1985
- Angioarchitecture in Experimental HydrocephalusPediatric Neurosurgery, 1985
- Pre- and Postoperative Evaluation of Cerebral Blood Flow in Low-Pressure HydrocephalusJournal of Neurosurgery, 1969