Downregulation of 14-3-3σ Prevents Clonal Evolution and Leads to Immortalization of Primary Human Keratinocytes
Open Access
- 29 May 2000
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 149 (5), 1117-1130
- https://doi.org/10.1083/jcb.149.5.1117
Abstract
In human epidermal keratinocytes, replicative senescence, is determined by a progressive decline of clonogenic and dividing cells. Its timing is controlled by cKeywords
This publication has 72 references indexed in Scilit:
- Unlimited Mileage from Telomerase?Science, 1999
- Cellular senescence and cancerThe Journal of Pathology, 1999
- Differential expression and functionally co-operative roles for the retinoblastoma family of proteins in epidermal differentiationOncogene, 1998
- Association of basonuclin with ability of keratinocytes to multiply and with absence of terminal differentiation.The Journal of cell biology, 1994
- Location of stem cells of human hair follicles by clonal analysisCell, 1994
- The epidermal stem cell: an overviewSeminars in Developmental Biology, 1993
- Molecular Cloning and Expression of the Transformation Sensitive Epithelial Marker StratifinJournal of Molecular Biology, 1993
- Three clonal types of keratinocyte with different capacities for multiplication.Proceedings of the National Academy of Sciences, 1987
- Permanent Coverage of Large Burn Wounds with Autologous Cultured Human EpitheliumNew England Journal of Medicine, 1984
- Epidermal Stem CellsJournal of Investigative Dermatology, 1983