Insulin-degrading Enzyme Regulates Extracellular Levels of Amyloid β-Protein by Degradation
Open Access
- 1 December 1998
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 273 (49), 32730-32738
- https://doi.org/10.1074/jbc.273.49.32730
Abstract
No abstract availableKeywords
This publication has 36 references indexed in Scilit:
- Proteolytic Degradation of Alzheimer's Disease Amyloid β-Peptide by a Metalloproteinase from Microglia CellsJournal of Neurochemistry, 2002
- Insulin-Degrading Enzyme Does Not Require Peroxisomal Localization for Insulin DegradationEndocrinology, 1997
- Overexpression of Insulin Degrading Enzyme: Cellular Localization and Effects on Insulin SignalingBiochemical and Biophysical Research Communications, 1997
- Degradation of Amyloid β-Protein by a Serine Protease-α2-Macroglobulin ComplexPublished by Elsevier ,1996
- Expression, purification, and characterization of the Kunitz-type proteinase inhibitor domain of the amyloid β-protein precursor-like protein-2Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1994
- Alzheimer's β‐amyloid peptide specifically interacts with and is degraded by insulin degrading enzymeFEBS Letters, 1994
- Cell Biology of the Amyloid beta-Protein Precursor and the Mechanism of Alzheimer's DiseaseAnnual Review of Cell and Developmental Biology, 1994
- The carboxy terminus of the .beta. amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's diseaseBiochemistry, 1993
- Amyloid β-peptide is produced by cultured cells during normal metabolismNature, 1992
- An insulin epidermal growth factor-binding protein from Drosophila has insulin-degrading activity.The Journal of cell biology, 1989