Theoretical decrease in systemic availability with decrease in input rate at steady‐state for first‐pass drugs
- 1 July 1985
- journal article
- research article
- Published by Wiley in Biopharmaceutics & Drug Disposition
- Vol. 6 (3), 341-343
- https://doi.org/10.1002/bdd.2510060309
Abstract
No abstract availableKeywords
This publication has 7 references indexed in Scilit:
- Flow dependence of first-order uptake of substances by heterogeneous perfused organsJournal of Theoretical Biology, 1980
- A METHOD OF DETERMINING INTRINSIC HEPATIC CLEARANCE FROM THE FIRST-PASS EFFECTClinical and Experimental Pharmacology and Physiology, 1980
- Current models of hepatic eliminationGastroenterology, 1979
- Hepatic elimination of flowing substrates: The distributed modelJournal of Theoretical Biology, 1978
- Enzymatic elimination of substrates flowing through the intact liverJournal of Theoretical Biology, 1976
- Clearance concepts in pharmacokineticsJournal of Pharmacokinetics and Biopharmaceutics, 1973