Plasma Thromboplastin Component (PTC) Potency of Plasma Fractions.
- 1 May 1953
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 83 (1), 69-71
- https://doi.org/10.3181/00379727-83-20268
Abstract
The plasma thromboplastin component (PTC) factor is concd, in fractions III and IV-1 of the plasma proteins. Small quantities are found in fractions I and IV-4, none in fractions II and V. Since fraction II contains thrombin and fraction IV-1 is poorly soluble, neither is suitable for intraven. administration. The intraven. administration of fraction IV produced marked shortening of the whole blood coagulation time and reduction in residual serum prothrombin in PTC deficiency. The results appear superior to those which can be achieved by the intraven. administration of fraction I in hemophilia.Keywords
This publication has 3 references indexed in Scilit:
- Plasma Thromboplastin Component (PTC) A Hitherto Unrecognized Blood Coagulation Factor Case Report of PTC DeficiencyBlood, 1953
- Plasma Throinboplastin Component (PTC) Deficiency: A New Disease Resembling HemophiliaExperimental Biology and Medicine, 1952
- Preparation and Properties of Serum and Plasma Proteins. IV. A System for the Separation into Fractions of the Protein and Lipoprotein Components of Biological Tissues and Fluids1a,b,c,dJournal of the American Chemical Society, 1946