CIRCADIAN RHYTHM OF CORTICOSTERONE LEVELS IN RAT BRAIN
- 31 January 1976
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 68 (2), 235-239
- https://doi.org/10.1677/joe.0.0680235
Abstract
SUMMARY: In the present study the circadian changes which occur in the levels of corticosterone in the brain and plasma in Sprague–Dawley rats are reported. The levels of corticosterone in the brain were found to have a daily trough and crest with timing similar to that observed for the plasma steroid. In addition, the effect of histamine stress on the corticosterone content of the particulate and the soluble fractions at the trough and crest was examined. The levels of both brain fractions were significantly higher 20 min after histamine injection. The time of day at which the stress was applied was not a significant factor in the magnitude of the stress response.This publication has 3 references indexed in Scilit:
- Effects of Bilateral Adrenalectomy and Continuous Light on the Circadian Rhythm of Corticotropin in Female Rats1Endocrinology, 1968
- Effects of Diurnal Variation in Plasma Corticosterone Levels on Adrenocortical Response to Stress.Experimental Biology and Medicine, 1967
- PHASE RELATIONS OF 24-HOUR PERIODICITIES IN BLOOD CORTICOSTERONE, MITOSES IN CORTICAL ADRENAL PARENCHYMA, AND TOTAL BODY ACTIVITY1,2Endocrinology, 1959