Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy
Open Access
- 1 January 2000
- journal article
- research article
- Published by Wiley in Mediators of Inflammation
- Vol. 11 (5), 299-306
- https://doi.org/10.1080/09629350210000015700
Abstract
Background: The model of pleurisy induced by carrageenan exhibits a biphasic response (4 and 48 h) and permits the quantification of exudate, cell migration and certain enzymes such as myeloperoxidase (MPO) and adenosine-deaminase (ADA) that are markers of activated leukocytes.Keywords
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