Demonstration of a main immunogenic region on acetylcholine receptors from human muscle using monoclonal antibodies to human receptor
- 11 July 1983
- journal article
- Published by Wiley in FEBS Letters
- Vol. 158 (1), 116-118
- https://doi.org/10.1016/0014-5793(83)80688-7
Abstract
Eleven cloned hybridomas which secrete antibodies to acetylcholine receptors from human muscle have been prepared. All of these monoclonal antibodies to have the same basic specificity as shown by competition for binding to the main immunogenic region on the receptor, but these antibodies differ in fine specificity as shown by reaction with denatured receptor subunits and interspecies cross‐reaction.Keywords
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