Decreased conversion of tyrosine to catecholamines in the brain of rats treated with p-chlorophenylalanine
- 1 February 1973
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 25 (2), 101-103
- https://doi.org/10.1111/j.2042-7158.1973.tb10601.x
Abstract
Repeated treatment with p-chlorophenylalanine (100 mg kg−1) daily for 5 days impairs the transport of amino-acids from plasma into the brain and decreases the rate of conversion of [3H]tyrosine to [3H] catecholamines in the rat brain. The possible mechanisms involved are discussed.Keywords
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