Vasoactive Intestinal Polypeptide Immunopositive Neurons in the Paraventricular Nucleus of Homozygous Brattleboro Rats
- 1 January 1986
- journal article
- research article
- Published by S. Karger AG in Neuroendocrinology
- Vol. 42 (1), 88-90
- https://doi.org/10.1159/000124254
Abstract
Colchicine treatment reveals a population of vasoactive intestinal polypeptide (VIP) positive cell bodies in the hypothalamic paraventricular nucleus (PVN) of the vasopressin-deficient Brattleboro rat. These immunoreactive perikarya in the PVN cannot be detected in colchicine-treated Long-Evans animals. When Brattleboro rats are administered vasopressin, there is a significant decrease in the number of VIP-immunopositive cell bodies in the PVN. Evidently, an alteration in the synthesis and/or release of VIP occurs in the absence of the antidiuretic hormone.Keywords
This publication has 5 references indexed in Scilit:
- Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion.Proceedings of the National Academy of Sciences, 1985
- Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.Journal of Histochemistry & Cytochemistry, 1981
- Vasoactive intestinal peptide (VIP): Brain distribution, subcellular localization and effect of deafferentation of the hypothalamus in male ratsBrain Research, 1979
- Vasoactive intestinal polypeptide: Release into hypophyseal portal bloodLife Sciences, 1979
- Luteinizing Hormone Releasing Activity in Different Parts of Rabbit and Dog BrainEndocrinology, 1965