A model for hyperphenylalaninaemia due to tetrahydrobiopterin deficiency
- 15 April 1985
- journal article
- research article
- Published by Wiley in Journal of Inherited Metabolic Disease
- Vol. 9 (1), 4-14
- https://doi.org/10.1007/bf01813895
Abstract
A model for tetrahydrobiopterin deficiency in mice is described. Elevated levels of phenylalanine produced in the model were shown to be dramatically reduced after injection of tetrahydrobiopterin. A comparison of several reduced pterins for their efficacy in the system is described. The unnatural S isomer of tetrahydrobiopterin was shown to be active in the system.This publication has 28 references indexed in Scilit:
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