The human genes for calbindin 27 and 29 kDa proteins are located on chromosomes 8 and 16, respectively
- 1 January 1989
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 52 (1-2), 85-87
- https://doi.org/10.1159/000132847
Abstract
Genomic clones coding for the brain calcium-binding protein, calbindin 29 kDa, were isolated from a human library. A fragment containing exon 2 was used as a probe to investigate the presence of the gene in human × rodent somatic cell hybrids. The gene was unambiguously assigned to chromosome 16. The closely-related calbindin 27 kDa gene was previously assigned to chromosome 8. These two genes, deriving from a common ancestor, thus appear to have been separated during vertebrate evolution.Keywords
This publication has 10 references indexed in Scilit:
- Cloning and chromosomal location of human genes inducible by type I interferonSomatic Cell and Molecular Genetics, 1988
- Human 27‐kDa calbindin complementary DNA sequenceEuropean Journal of Biochemistry, 1987
- Calretinin: a gene for a novel calcium-binding protein expressed principally in neurons [published erratum appears in J Cell Biol 1990 May;110(5):1845]The Journal of cell biology, 1987
- Calbindin in vertebrate classes: Immunohistochemical localization and Western blot analysisGeneral and Comparative Endocrinology, 1987
- Rat brain synthesizes two ‘vitamin D-dependent’ calcium-binding proteinsBrain Research, 1985
- Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencingGene, 1984
- A technique for radiolabeling DNA restriction endonuclease fragments to high specific activityAnalytical Biochemistry, 1983
- DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences, 1977
- Screening λgt Recombinant Clones by Hybridization to Single Plaques in SituScience, 1977
- Vitamin D 3 -Induced Calcium-Binding Protein in Chick Intestinal MucosaScience, 1966