Effect of Uterine Extracts and Uterine or Ovarian Blood Vessel Ligations on Ovarian Function of Ewes

Abstract

Injections of ether-soluble extracts or lyophilized homogenates of uteri from ewes at various stages of the estrous cycle failed to promote regression of corpora lutea in hysterectomized ewes. Regression of corpora lutea, estrus and subsequent ovulation in the cycling ewe was prevented by hysterectomy performed as late as the calculated last day of the cycle. Bilateral ligation of middle uterine arteries and veins in intact nongravid ewes resulted in extended luteal maintenance in seven of eight ewes, while unilateral ligation resulted in prolonged luteal maintenance in only one of six ewes. Bilateral or unilateral ligation of the middle uterine arteries alone, excluding the vein, did not alter estrous cycles. Ligation of major ovarian vessels resulted in regression of corpora lutea in 29 of 37 hysterectomized ewes. Blood supply was reestablished following ligation and an increased number of ovulations resulted. Copyright © 1966. American Society of Animal Science . Copyright 1966 by American Society of Animal Science