DIE METABOLITE IM MENSCHLICHEN HARN NACH VERABREICHUNG VON 17α-AETHINYL-19-NORTESTOSTERON (NORAETHISTERON)
- 1 May 1961
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 37 (1), 14-18
- https://doi.org/10.1530/acta.0.0370014
Abstract
The metabolites of 17α-ethynyl-19-nortestosterone were determined in the urine of 5 postmenopausal women. Only a small fraction of the unchanged compound and a small amount of Δ4-3-ketosteroids which still carry the ethynyl group at carbon 17 as well as traces of steroid alcohols are excreted. Ethinyloestradiol was identified by paper chromatography. The inhibitory effect of the 17-alkylation on steroid metabolism is discussed.Keywords
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