Clinical Significance of the Multiple Sclerosis Functional Composite

Abstract
THE MULTIPLE Sclerosis Functional Composite (MSFC) is a multidimensional composite measure for multiple sclerosis (MS) clinical trials that was recommended by the National Multiple Sclerosis Society (NMSS) Clinical Outcomes Assessment Task Force.1 The MSFC was developed in response to the following consensus statement issued by participants in an international workshop on outcomes assessment: