Alpha‐I‐antitrypsin (Pi) phenotypes in Lyon, France: departure from Hardy‐Weinberg equilibrium
- 1 August 1977
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 12 (2), 77-79
- https://doi.org/10.1111/j.1399-0004.1977.tb00905.x
Abstract
The validity of the Hardy-Weinberg euilibrium for Pi phenotypes was tested in a population of 1653 randomly selected, healthy blood donors in Lyon, France. A significant departure from the equilibrium was found, with an excess of FF and SS homozygotes and a deficiency of FM heterozygotes.This publication has 4 references indexed in Scilit:
- Alpha-1-Antitrypsin phenotypes in Lyon, FranceHuman Genetics, 1977
- The Pi System: Its Study by means of Thin-Layer-Gel Electrofocusing in Polyacrylamide GelPublished by Elsevier ,1975
- The polymorphism of “prealbumins” and α1-antitrypsin in human seraClinica Chimica Acta; International Journal of Clinical Chemistry, 1967
- On a Matching Problem Arising in GeneticsThe Annals of Mathematical Statistics, 1949