Endocrine Therapy of Functional Menometrorrhagia and Ovarian Sterility IV. One-Two Cyclic Therapy with Equine and Chorionic Gonadotropins1

Abstract

IN VIEW OF THE LACK OF EVIDENCE, secured from the studies of the preceding communication, that the cyclic administration of equine gonado’ tropins affords any significant salvage in anovulatory ovarian failure, and because the theoretical and experimental considerations reviewed previously indicated that in the cases of the monkey and woman augmentation or synergism1 of equine gonadotropin with chorionic gonadotropin was doubtlessly necessary for full supplementation of pituitary deficiency, the present study was made. It is concerned with the assessment of effectiveness of a system of one'two cyclic therapy with equine and chorionic gonadotropins. The rationale of this form of therapy has been considered in detail in the preceding communication.