Infections with Herpes Simplex Viruses

Abstract

IN the 12 years since the last review of herpes simplex virus (HSV) infections in these pages,¹ there have been substantial advances in our knowledge of the clinical manifestations, pathogenesis, and therapy of these infections. The epidemic of sexually transmitted HSV infection that has occurred in the past decade, the concomitant increase in neonatal herpes, and the increasing recognition of the diversity and morbidity of HSV infections in immunocompromised patients have heightened awareness of these agents among medical professionals, the public, and the press.^{2 3 4 5 6} The development of clinically useful antiviral therapy for HSV infections has made recognition of the clinical . . .