Record of experiments illustrative of the symptomatology and degenerations owing lesions of the cerebellum and its peduncles and related structures in nkeys

Abstract

Series of experiments, which are recorded in this paper, was undertaken for the se of ascertaining the effects, temporary or permanent, following total or partial ation of the cerebellum and section of its peduncles; and more especially with a of determining by microscopic examination the position and relations of the dary degenerations which might be induced. But, before this research had made progress, the works of Luciani (1) and Marchi (2) on a similar subject had red. Until Luciani, originally in the “Prima Memoria” [1884], and more tly in his work, “II Cervelletto” [1891], published the results of his investigation, comparatively few experiments had been recorded on the cerebellum of monkeys. only previous experiments were those of Ferrier (3) on the electrical excitability of the cerebellar cortex, supplemented by a study of the effects of localised lesio These were few in number, and were confined merely to observation of the tempora phenomena, the animals being killed soon after the operation, so as to obviate extension from the primary lesion by secondary inflammation. The experiments Luciani, therefore, form, at present, the only basis of facts with which our observations may be strictly compared. We do not consider it necessary to refer to the vast literature relating to the effects of lesions of the cerebellum in other animals, which are sufficiently well known tell students of physiology. We therefore limit our references to those of more recent investigators working according to similar methods.