RIFT VALLEY FEVER VIRUS HEPATITIS LIGHT AND ELECTRON MICROSCOPIC STUDIES IN THE MOUSE
- 1 June 1963
- report
- Published by Defense Technical Information Center (DTIC)
- Vol. 42 (5), 587-+
- https://doi.org/10.21236/ad0410394
Abstract
Rift Valley fever virus produces a necrotizing hepatitis in mice that is similar to certain other virus hepatitides. The virus infects the hepatic parenchymal cells and new virus is formed in the cytoplasm within a membrane- limited system resembling the Golgi apparatus. Unique structural alterations of the ergastoplasm are associated with this process and may be manifestations of metabolic dysfunction. The acidophilic nuclear inclusion is not formed of virus matrix or virus particles and may represent a degenerative phenomenon. Changes in the Kupffer cells follow infection of the parenchymal cells.Keywords
This publication has 11 references indexed in Scilit:
- Electron microscope study of mouse liver infected by ectromelia virusJournal of Ultrastructure Research, 1962
- The pathogenesis of Rift Valley fever in lambs.1962
- EFFECT OF A MURINE HEPATITIS VIRUS ON LIVER - AN ANATOMIC AND HISTOCHEMICAL STUDY1962
- AN ELECTRON MICROSCOPIC STUDY OF VIRAL HEPATITIS IN MICE1962
- KUPFFER CELL REACTION IN MURINE AND HUMAN VIRAL HEPATITIS, WITH PARTICULAR REFERENCE TO ORIGIN OF ACIDOPHILIC BODIES1962
- STRUCTURE AND DEVELOPMENT OF VIRUSES AS OBSERVED IN THE ELECTRON MICROSCOPEThe Journal of Experimental Medicine, 1961
- BIOLOGICAL AND BIOCHEMICAL BASIS FOR CELL INJURY BY ANIMAL VIRUSES1961
- STRUCTURE AND DEVELOPMENT OF VIRUSES AS OBSERVED IN THE ELECTRON MICROSCOPEThe Journal of Experimental Medicine, 1961
- Cytological and cytochemical studies on the liver cells of yellow‐fever‐infected rhesus monkeysThe Journal of Pathology and Bacteriology, 1960
- RIFT-VALLEY FEVER VIRUS IN MICE .4. INCOMPLETE VIRUS - ITS PRODUCTION AND PROPERTIES1956