Transplantation of Marrow from an Unrelated Donor to a Patient with Acute Leukemia
- 4 September 1980
- journal article
- case report
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 303 (10), 565-567
- https://doi.org/10.1056/nejm198009043031007
Abstract
MARROW transplantation between genotypically HLA-identical siblings has an established and expanding place in the management of leukemia and aplastic anemia.1 2 3 The majority of patients, unfortunately, do not have such siblings. Experience with marrow donors other than HLA-identical siblings has been limited. Recently it has been demonstrated that for patients with acute leukemia, marrow transplantation performed during remission improves the probability of disease-free survival.1 , 2 , 4 , 5 In view of this new therapeutic outlook, the determination of new criteria for donor selection has become clinically relevant. We report here a successful marrow transplantation in a patient with acute lymphoblastic leukemia in second remission; the . . .Keywords
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