Translating the Diabetes Prevention Program Lifestyle Intervention for Weight Loss Into Primary Care

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Abstract
An estimated 69% of US adults are overweight or obese,1 and those with modifiable cardiometabolic risk factors are a critical target group for intervention.2,3 Lifestyle modification focused on modest (5%-10%) weight loss and moderate-intensity physical activity can significantly reduce the incidence of type 2 diabetes mellitus (DM) (as much as 58% as shown in the Diabetes Prevention Program [DPP]) and cardiometabolic risk factors in high-risk individuals,4-6 with benefits sustained for at least 10 years.7 Evidence-based guidelines therefore recommend effective lifestyle intervention for weight management and disease prevention.8,9