Concise Review: Adipose-Derived Stromal Vascular Fraction Cells and Platelet-Rich Plasma: Basic and Clinical Implications for Tissue Engineering Therapies in Regenerative Surgery
Open Access
- 22 February 2012
- journal article
- review article
- Published by Oxford University Press (OUP) in Stem Cells Translational Medicine
- Vol. 1 (3), 230-236
- https://doi.org/10.5966/sctm.2011-0054
Abstract
Cell-based therapy and regenerative medicine offer a paradigm shift in regard to various diseases causing loss of substance or volume and tissue or organ damage. Recently, many authors have focused their attention on mesenchymal stem cells for their capacity to differentiate into many cell lineages. The most widely studied types are bone marrow mesenchymal stem cells and adipose-derived stem cells (ADSCs), which display similar results. Based on the literature, we believe that the ADSCs offer advantages because of lower morbidity during the harvesting procedure. Additionally, platelet-rich plasma can be used in this field for its ability to stimulate tissue regeneration. The aims of this article are to describe ADSC preparation and isolation procedures, preparation of platelet-rich plasma, and the application of ADSCs in regenerative plastic surgery. We also discuss the mechanisms and future role of ADSCs in cell-based therapy and tissue engineering.Keywords
This publication has 62 references indexed in Scilit:
- The Tunica Adventitia of Human Arteries and Veins As a Source of Mesenchymal Stem CellsStem Cells and Development, 2012
- Regional Anatomic and Age Effects on Cell Function of Human Adipose-Derived Stem CellsAnnals of Plastic Surgery, 2008
- Role of Gender and Anatomical Region on Induction of Osteogenic Differentiation of Human Adipose-derived Stem CellsAnnals of Plastic Surgery, 2008
- Characterization of adipose tissue-derived cells isolated with the Celution™ systemCytotherapy, 2008
- Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation: Supportive Use of Adipose-Derived Stem/Stromal CellsAesthetic Plastic Surgery, 2007
- Cell-Assisted Lipotransfer: Supportive Use of Human Adipose-Derived Cells for Soft Tissue Augmentation with LipoinjectionTissue Engineering, 2006
- Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statementCytotherapy, 2006
- Genetic and epigenetic control of skeletal muscle developmentAnnals of Anatomy - Anatomischer Anzeiger, 2005
- Cell Surface and Transcriptional Characterization of Human Adipose‐Derived Adherent Stromal (hADAS) CellsThe International Journal of Cell Cloning, 2005
- Multilineage Cells from Human Adipose Tissue: Implications for Cell-Based TherapiesTissue Engineering, 2001